KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
15.45
Human Site:
S443
Identified Species:
24.29
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S443
S
S
S
A
P
A
Q
S
S
P
S
S
G
H
E
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S443
S
S
S
A
P
A
Q
S
S
P
S
S
G
H
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
X191
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
Dog
Lupus familis
XP_534537
1097
121903
A430
P
V
A
V
P
I
R
A
G
V
P
S
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S442
S
S
S
A
P
A
Q
S
S
P
S
G
G
H
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S434
S
S
S
A
P
A
Q
S
S
P
G
N
G
H
E
Chicken
Gallus gallus
XP_419666
1136
127431
S449
P
P
P
V
Q
P
Q
S
S
P
G
N
G
H
E
Frog
Xenopus laevis
NP_001087838
1118
125984
P438
A
T
S
T
Q
S
A
P
G
S
N
H
E
M
L
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
V429
S
Q
L
S
A
T
T
V
T
T
V
T
Q
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Q432
A
A
A
A
H
Q
Q
Q
H
Q
H
Q
Q
S
K
Honey Bee
Apis mellifera
XP_395146
1137
124999
V479
P
P
P
A
Y
P
P
V
N
S
V
G
T
T
S
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
G519
I
P
S
Q
M
G
G
G
N
V
V
Q
I
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
L142
G
N
A
Q
L
P
Q
L
S
P
G
Q
Y
S
I
Red Bread Mold
Neurospora crassa
P38679
598
67999
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
0
20
N.A.
93.3
N.A.
N.A.
86.6
46.6
6.6
6.6
N.A.
13.3
6.6
0
6.6
P-Site Similarity:
100
100
0
40
N.A.
93.3
N.A.
N.A.
93.3
53.3
33.3
26.6
N.A.
40
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
20
40
7
27
7
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
7
7
7
14
0
20
14
34
0
0
% G
% His:
0
0
0
0
7
0
0
0
7
0
7
7
0
34
0
% H
% Ile:
7
0
0
0
0
7
0
0
0
0
0
0
7
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% K
% Leu:
0
0
7
0
7
0
0
7
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
14
0
7
14
0
0
0
% N
% Pro:
20
20
14
0
34
20
7
7
0
40
7
0
0
0
7
% P
% Gln:
0
7
0
14
14
7
47
7
0
7
0
20
14
7
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
34
27
40
7
0
7
0
34
40
14
20
20
0
14
7
% S
% Thr:
0
7
0
7
0
7
7
0
7
7
0
7
7
14
7
% T
% Val:
0
7
0
14
0
0
0
14
0
14
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _